Top 15 Best e-Prescribing Software

E-prescribing is quickly changing the way healthcare providers manage prescriptions. Instead of relying on manual methods that often cause delays, confusion, and compliance issues, more professionals are turning to digital tools that simplify the process. With e-prescribing software, doctors can send prescriptions directly to pharmacies, reducing the risk of errors and saving time for both patients and providers. This shift not only improves accuracy but also helps patients stay on track with their medications. They can get reminders and helpful information about their prescriptions, which makes it easier to understand what they’re taking and why.

With e-prescribing software, patients feel more informed and involved in their care, which often leads to better outcomes and an overall boost in quality of life. As more healthcare professionals adopt this approach, the benefits are becoming clear: fewer mistakes, more efficient workflows, and stronger patient-provider relationships.

Top 15 Best e-Prescribing Software

1. Practice Fusion

Practice Fusion helps healthcare providers manage prescriptions in one place. This includes routine medications, controlled substances, and those that need prior authorization. The platform connects with over 500 lab and imaging centers. Providers can quickly order tests and share results with patients. It also includes helpful tools like clinical alerts, Electronic Prior Authorization (ePA), and Electronic Prescribing of Controlled Substances (EPCS). These features support safe and efficient patient care. Providers can choose from multiple pharmacy options and easily handle prescription tasks.

Pricing

Pricing starts at $199 per provider each month. You can request a custom quote based on your practice’s needs.

2. AdvancedMD

AdvancedMD includes helpful tools for managing prescriptions and medication-related tasks. You can access a drug reference database, handle electronic prior authorizations (EPCS), check medication histories, review formularies, and explore different pharmacy options. These features aim to support patient safety while simplifying the prescription process. It comes with an easy-to-navigate interface that makes handling administrative duties less of a hassle, while also supporting better patient care and smoother workflows.

Pricing

Contact vendor for pricing

3. Tebra

Tebra (formerly Kareo EHR) is a cloud-based EMR and practice management system that helps healthcare professionals simplify everyday tasks and focus more on patient care. With its e-prescription tool, you can quickly send prescriptions, reduce the risk of medication errors, and cut down on the hassles of manual entry. The system also lets you view medication history and keep track of patient records  all within your existing workflow.

Pricing

To get started, there’s a one-time setup fee of $500. If you plan to prescribe controlled substances electronically, you’ll also need to pay a $75 application fee. In addition, each authorized user pays a $50 annual fee.

4. Rcopia

Rcopia, created by DrFirst, helps doctors send prescriptions directly to pharmacies through electronic channels. It includes helpful tools like access to a patient’s medication history and alerts for potential allergies or drug interactions. The software also connects with EHR systems, making it easier for healthcare providers to work within their existing workflows. In addition, Rcopia allows for electronic prescribing of controlled substances (EPCS), which adds an extra layer of convenience for prescribers.

Pricing
For pricing details, you’ll need to reach out to the company directly for a quote.

5. MDToolbox

MDToolbox is a cloud-based e-prescribing software that also comes with a mobile version, making it convenient for healthcare providers who need flexibility while managing prescriptions. Its main module, MDToolbox Rx, allows prescribers to send electronic prescriptions for both controlled and non-controlled medications. This makes it suitable for a variety of medical practices, from clinics to larger healthcare facilities. It simplifies daily prescribing activities while keeping everything digital and compliant.

Pricing

• E-Prescribe Pro: $28/month with an annual subscription or $30/month when paid monthly
• E-Prescribe Complete: $35/month with an annual subscription or $38/month when billed monthly

Contact the MDToolbox team for a detailed breakdown.

6. PrognoCIS EMR

PrognoCIS offers a patient portal that helps organizations easily share lab results, prescriptions, and statements with clients. It also sends reminders to patients for their upcoming appointments, making communication more efficient. With PrognoCIS EMR, healthcare providers can access a patient’s full medical history in one place. Additionally, the system features a Pediatric Conversion Calculator, where the patient’s weight is automatically filled in based on the data entered during a vitals check. This feature calculates the correct dosage, eliminating guesswork and reducing the chances of errors.

Pricing

Contact directly for quote.

7. Drchrono EHR

Drchrono’s EHR system includes integrated Electronic Prescribing of Controlled Substances (EPCS), allowing you to send prescriptions from any device with ease. It ensures full compliance with DEA, NIST, and Surescripts standards, offering top-notch security and fraud protection for every prescription. The platform also features a simple two-factor soft token authentication for added security.

Pricing

Drchrono offers various EHR feature packages that are billed on a per-provider basis. You can also improve your system with additional features for as low as $20 per provider each month.

8. ChARM Health

The e-Prescription feature in CharmHealth EHR offers a simple, straightforward workflow that connects you with over 70,000 pharmacies across the United States. It allows you to send electronic prescriptions and handle refill requests easily. The integrated drug database lets you quickly search for medications by name, with the option to filter results based on strength, form, and route. The system also provides instant alerts for potential issues such as drug interactions, allergies, and drug-food conflicts.

To make prescribing even more convenient, you can record a patient’s preferred pharmacy once. This means you won’t have to search for a pharmacy each time you send a prescription.

Pricing 

For pricing, there are three options available:

• Free
• Encounter plan ($0.50 per encounter per month)
• Provider plan ($350 per provider per month)

For more details on which plan fits your practice, it’s best to contact the vendor directly.

9. patientNOW

With patientNOW, you can quickly create a list of frequently prescribed medications, including their dosage and additional notes, alongside a list of nearby pharmacies. Once set up, you can easily select a pharmacy and add medications with just a click. patientNOW ensures you have instant access to both current and past prescriptions, providing reliable and up-to-date information about your patients’ medications. The platform also sends notifications for potential drug interactions and allergy warnings, as well as specific precautions for older adults, children, pregnant women, and breastfeeding mothers. You can add custom instructions for medications in a designated note field for further clarity.

Pricing

For pricing details, contact the vendor.

10. DoseSpot