Top 30 Best Oncology Management Software Platforms

Oncology is one of the most complex medical fields. It focuses on the diagnosis, treatment, and prevention of cancer. Managing cancer care involves many moving parts, from planning chemotherapy and radiation to handling drug billing, lab coordination, and compliance standards. These tasks can overwhelm general electronic health records, which often lack the depth and precision oncology demands. Oncology management software offer purpose-built tools that simplify complex tasks like building chemo protocols, scheduling infusion chairs, calculating doses, and coordinating across teams. These systems also improve billing and prescription workflows, add safety checks, and support communication through patient portals. For modern oncology practices aiming to deliver accurate, safe, and efficient care, these platforms have become essential.

Top 30 Best Oncology Management Software Platforms 

2. CureMD

CureMD offers a cloud-based oncology practice management and electronic health record system built to support the day-to-day operations of cancer care providers. It brings chemotherapy management into one system, allowing physicians to coordinate treatments and prescriptions more efficiently. The platform helps reduce billing errors and simplifies how practices track patient balances, easing revenue-related bottlenecks. It includes tools for documenting adverse events in line with NCI’s CTCAE guidelines, supports forecasting for drug utilization, and manages clinical orders from start to finish. Physicians also benefit from therapeutic class–based drug indexes, PACS/DICOM imaging capabilities, and advanced reporting tools that improve visibility into patient outcomes and practice performance.

Pros

• Simplifies medical record handling for cancer care providers
• Offers mobile access for more flexible patient engagement

Cons

• Users may need time and training to adapt to the system
• May not fully meet complex customization requirements for some practices.

3. Athenahealth

athenahealth EMR is a cloud-based system built for small to mid-sized medical practices. It provides a secure environment for updating and accessing patient records remotely. Healthcare providers can schedule appointments, track lab orders, and communicate with other professionals, helping to improve daily operations. The platform includes intuitive templates and interfaces that make it easier to enter patient details during consultations, which improves accuracy and keeps documentation up to date. This smooth exchange of information supports better collaboration between care teams.

Pros

• Generates detailed reports that help measure practice performance
• Supports population health tracking and care coordination

CONS

• Customer support could be more responsive and effective
• The patient portal sometimes crashes under heavy use

4. iKnowMed 

iKnowMed EHR makes it easier for oncology practices to stay organized and work efficiently. Built in partnership with oncologists, it adapts easily into everyday clinical routines without causing major disruptions. Its simple layout supports quick navigation and allows users to access patient information securely from any device. Clinicians can also personalize their dashboards to see the most relevant data at a glance. The software includes a Care Value Plus tool, which helps doctors choose treatment options backed by medical evidence, while also providing important clinical and billing details during consultations.

Pros:

• User-friendly interface makes navigation easy
• Integrates into existing workflows with minimal interruption
• Offers evidence-based treatment guidance with Care Value Plus

Cons:

• Initial setup and use can be difficult for users with limited tech skills

5. ARIA Oncology 

ARIA Oncology management software supports cancer care teams with a structured digital environment that simplifies treatment documentation and enhances the tracking of patient progress. It allows clinicians to monitor cancer staging, manage treatment plans, and evaluate long-term outcomes based on the widely recognized AJCC guidelines. The system includes automated cancer staging tools and integrates key clinical components such as pharmacy and laboratory data into one interface, enabling faster clinical decisions. Its graphing capabilities allow practitioners to quickly visualize treatment progress and changes in a patient’s condition.

ARIA® also works in partnership with OncoLog Cancer Registry to aid clinical research. This collaboration enables deeper analysis of treatment trends, complications, and outcomes, using both prospective and retrospective data.

Pros

• Quick access to comprehensive patient data.
• Simple document upload process.
• Strong integration with other software systems.
• Frequent updates and a high level of customization.

Cons

• Image uploads may take longer than expected.
• System performance can drop after updates, requiring a restart that adds to downtime.

6.  MOSAIQ EMR 

MOSAIQ, developed by Elekta, is a HIPAA-compliant and ONC-ATCB-certified software used widely in oncology practices. It combines practice management and electronic medical records to support both medical and radiation oncology. The system connects clinical, administrative, and billing tasks into one interface, making it easier for healthcare providers to manage daily operations and patient treatment. Its medical oncology module supports chemotherapy programs and maintains direct communication with pharmacies, labs, and cancer registries. On the radiation side, it offers tools that simplify clinical decisions through automated workflows and treatment planning.

Pros:

• Offers a high level of customization for various features
• Strong performance in practice management and scheduling
• Combines multiple functions into a single platform
• Well-structured clinical notes
• Includes a helpful predictive maintenance tool

Cons:

• Reporting capabilities are somewhat limited
• The software takes a long time to load during start-up

7. PrognoCIS EMR 

PrognoCIS helps oncologists handle the complexities of cancer care with tools that simplify diagnosis, treatment, and patient interaction. Its EHR platform comes with pre-built templates for various cancer screenings and procedures, including bone marrow, endoscopic, needle, skin, and surgical biopsies. The system also offers treatment plan templates for therapies such as immunotherapy, radiation, targeted therapy, and different types of transplants. Other included modalities cover angiogenesis inhibitors, hyperthermia, and laser treatments in oncology. Doctors can easily connect with laboratories to view reports, receive test results, and send e-prescriptions, cutting down administrative time. The interface is user-friendly, and clinicians can access built-in patient education resources or upload their own materials, making it easier to involve patients in their care journey.

Pros:

• Helps doctors provide better patient care
• Saves time and improves workflow
• Keeps patient information secure

Cons:

• Slow load times can disrupt daily use
• The interface looks outdated when compared to newer platforms.

8. AdvancedMD

AdvancedMD brings together essential tools for medical practices, combining electronic health records, billing, and administrative support into a single system. It helps healthcare providers manage patient care more efficiently, with features that support everything from check-ins to billing. The platform includes a patient portal that allows for admissions, appointment scheduling, and access to medical records. Healthcare professionals can also use it on iOS devices, making it easier to work while away from the office. In addition to simplifying daily tasks, the software helps unify charts, prescriptions, and billing, making practice management less stressful and more organized.

Pros

• Includes a patient portal for easy access and communication
• Makes it easy to schedule and manage appointments
• Supports mobile use on iOS for flexible access

Cons

• Some users find the note templates difficult to modify
• System integration may require additional steps, which can be inconvenient.

9. Altai Oncology Suite

Altai Oncology Suite supports both cloud-based and on-premise setups, helping oncology clinics manage chemotherapy treatments with ease. It fits a variety of practice sizes, from solo physicians to larger cancer centers. Beyond oncology, rheumatologists also turn to this solution for managing infusion therapies. At its core, the platform brings together essential tools like a cancer registry module, inventory tracking, and QuickNote a note-entry system that allows providers to use pre-set templates when documenting clinical visits. The registry tool assists clinics in gathering cancer data, completing patient forms, and recording pathology reports. Meanwhile, QuickNote simplifies the process of documenting patient details, oncology history, and treatment notes using editable templates.

Pros

• Easy-to-navigate interface makes it simple for users to find what they need
• Custom APIs are available for connecting with other systems

Cons

• New users may face a bit of a learning curve
• The scheduling feature could use more refinement for better functionality

10. MedSym 

MedSym Solutions provides an electronic health record and practice management system built specifically for oncology. It works well for both small, independent practices and larger healthcare organizations. While it includes standard EHR features found in many competing platforms, MedSym stands out for focusing heavily on its practice management capabilities. That’s where it attempts to add the most value, helping oncology teams handle daily operations with less friction and more control.

Pros

• Includes scheduling and billing tools that help simplify administrative tasks
• Offers templates that make it easier to document clinical details and patient notes

Cons

• New users may need time to get used to the platform
• Doesn’t integrate easily with some third-party systems.

11.  Oncentric 

Oncentric’s Oncology EMR supports oncology practices in handling the many moving parts of cancer care. It helps providers stay organized and attentive as they manage treatment schedules, document adverse events, and administer complex drug regimens. With built-in tools for treatment planning, dosage tracking, and drug forecasting, it becomes easier for oncologists to stay on top of every patient’s unique journey. The platform brings clinical insights into everyday care without getting in the way of workflow, helping care teams make quicker, well-informed decisions while minimizing errors. It also connects smoothly with in-office labs and drug cabinets, cutting down the time spent on coordination and helping staff stay focused on the patient.

Pros

• Supports clinical trial drug tracking
• Includes alerts for safety and drug interactions
• Provides ready-to-use templates for provider notes

Cons

• May require training to fully explore all clinical tools
• Can be resource-heavy for smaller practices without IT support.

12. Practo

Practo offers a clinic management solution that supports oncology practices in handling patient care from diagnosis to recovery. Built with features specific to cancer care, the platform simplifies how clinics manage treatment schedules, medical records, and communication. Oncologists can track chemotherapy sessions, lab results, and follow-up visits in a structured, easy-to-navigate system. Practo also fosters team coordination by allowing specialists to collaborate on patient cases, keeping all relevant information in one place.

Pros

• Supports treatment planning and follow-up tracking for oncology patients
• Encourages collaboration between specialists and departments.

Cons