Top 30 Best Healthcare File Sharing and Collaboration Platforms

In modern healthcare, improving patient care, increasing team productivity, and upholding regulatory compliance all depend on safe file sharing and productive communication. By using these technologies, physicians, administrators, and outside partners can securely share clinical data, documents, and photographs while adhering to HIPAA and GDPR regulations. Given the increasing demand for telehealth, data-driven insights, and remote coordination, selecting the appropriate platform can have a significant impact on results and operational success. This article highlights the Top 30 Best Healthcare File Sharing and Collaboration Platforms each evaluated on security, integration, user experience, auditability, and scalability. From enterprise-grade suites to nimble tools for small clinics, this list will guide you toward solutions that fit your organization’s needs.

Top 30 Best Healthcare File Sharing and Collaboration Platforms

Box for Healthcare

Box for Healthcare combines enterprise-grade file sharing with enhanced privacy controls tailored for HIPAA compliance.

• Key Features

• • Secure file storage with granular permissions
  • Audit logs and access reports
  • Integration with EHR systems and collaboration tools

• Pros & Cons

• • Pros: Highly secure; wide integration ecosystem
  • Cons: Advanced features can be costly

• Pricing
  Enterprise quotes based on user counts
• Expert Commentary
  “Box gives health systems the ability to collaborate across care teams while maintaining compliance.”
  — Dr. Folakemi Arinze, Clinical Informaticist
• Demo: Watch demo

Dropbox Business (Dropbox for Healthcare)

Dropbox Business with HIPAA-enabled configurations offers intuitive sharing, document organization, and collaborative editing suited for healthcare teams.

• Key Features

• • File versioning with recoverability
  • Smart sync and collaborative editing
  • HIPAA-compliant architecture

• Pros & Cons

• • Pros: Familiar interface; fast adoption
  • Cons: Audit capabilities slightly less robust

• Pricing
  Standard plans around $20/user/month
• Expert Commentary
  “Dropbox provides simplicity for busy clinicians needing to share and review documents quickly.”
  — Dr. Uche Okafor, Health IT Coordinator
• Demo: Watch demo

Google Workspace for Healthcare

Google Workspace enhances care coordination with secure Drive storage, shared docs, and collaboration tools adapted for healthcare use.

• Key Features

• • Secure file sharing and collaboration in Drive
  • Admin controls and data loss prevention
  • Gmail and Meet integration for telehealth

• Pros & Cons

• • Pros: Real-time collaboration; familiar productivity suite
  • Cons: Configuring HIPAA-compliance requires careful setup

• Pricing
  Google Workspace plans start at $12/user/month
• Expert Commentary
  “For health systems already using G Suite, this offers seamless file collaboration with strong security options.”
  — Yetunde Ojo, Clinical Systems Manager
• Demo: Watch demo

Microsoft OneDrive for Business / Microsoft 365

Microsoft 365 with OneDrive and SharePoint provides secure document management and collaborative features deeply integrated into hospital IT.

• Key Features

• • Enterprise-level encryption and access controls
  • Co-authoring, version history, and secure sharing
  • Teams and Planner integration for project coordination

• Pros & Cons

• • Pros: Familiar Office ecosystem; robust compliance features
  • Cons: May require admin configuration for healthcare settings

• Pricing
  Business plans begin at $8.25/user/month
• Expert Commentary
  “Microsoft 365 is a secure and effective way to centralize medical documentation and facilitate team coordination.”
  — Chinedu Umeh, Health IT Infrastructure Specialist
• Demo: Watch demo

ShareFile by Citrix

ShareFile offers professional-grade file sharing with secure transfers, e-signatures, and workflow automation tailored for healthcare.

• Key Features

• • HIPAA-ready encrypted file sharing
  • Role-based access and audit trails
  • Request files and e-signature forms

• Pros & Cons

• • Pros: Workflow tools like e-sign and secure links enhance care coordination
  • Cons: Interface is functional but less refined

• Pricing
  From $60/user/month (advanced plan)
• Expert Commentary
  “ShareFile combines security with workflow automation—especially valuable for credentialing and referral exchange.”
  — Dr. Ngozi Amadi, Clinical Workflow Specialist
• Demo: Watch demo

Egnyte for Healthcare

Egnyte supports secure file sharing and collaboration, with hybrid options that cater to large hospitals handling both cloud and on-prem data.

• Key Features

• • Centralized policy control and encryption
  • Local access sync and hybrid deployment
  • Audit reports with user activity logs

• Pros & Cons

• • Pros: Excellent for enterprise environments with legacy systems
  • Cons: Hybrid setup adds complexity

• Pricing
  starts around $20/user/month
• Expert Commentary
  “Egnyte offers secure collaboration while bridging cloud and local storage needs for hospitals.”
  — Oluchi Ejike, IT Compliance Officer
• Demo: Watch demo

Syncplicity by Axway

Syncplicity provides secure file sharing and collaboration with detailed admin control and audit capabilities, tailored for healthcare institutions.

• Key Features

• • Policy-driven access and real-time sync
  • Remote wipe and device security
  • Comprehensive audit logs

• Pros & Cons

• • Pros: Strong data governance with hybrid deployment
  • Cons: Advanced features require administration expertise

• Pricing
  Custom pricing based on deployment
• Expert Commentary
  “Syncplicity ensures healthcare compliance with minimal friction for users.”
  — Dr. Aisha Bello, Health IT Security Manager
• Demo: Watch demo

Tresorit

Tresorit offers end-to-end encrypted file sharing and collaboration that meets HIPAA standards, with a strong focus on patient data protection.

• Key Features

• • Zero-knowledge encryption
  • Granular access rights and expiry controls
  • Secure links and real-time syncing

• Pros & Cons

• • Pros: Exceptional security and privacy
  • Cons: Collaboration tools are less extensive

• Pricing
  From $12.50/user/month
• Expert Commentary
  “Tresorit provides peace of mind for healthcare sharing encrypted data effortlessly.”
  — Evelyn Igwe, Clinical Privacy Officer
• Demo: Watch demo

Nextcloud Hub (Healthcare Edition)

Nextcloud Hub is an open-source platform for file sharing and collaboration, with HIPAA-oriented features such as audit logs and end-to-end encryption.

• Key Features

• • Self-hosting or cloud deployment
  • Document editing, file versioning, and secure sharing
  • Compliance and governance add-ons

• Pros & Cons

• • Pros: Highly customizable and self-controlled
  • Cons: Setup and maintenance require IT resources

• Pricing
  Free self-hosted; enterprise plans by quote
• Expert Commentary
  “Nextcloud offers healthcare teams full control over data and compliance.”
  — Chuka Maduka, EHR Integration Officer
• Demo: Watch demo

Citrix ShareFile

ShareFile delivers secure document sharing, e-signature functionality, and workflow automation built to serve healthcare environments.

• Key Features

• • Encrypted file storage and transfer
  • Role-based permissions and file expiry links
  • Integrated e-signature requests and workflows

• Pros & Cons

• • Pros: Enhances secure collaboration and document workflows
  • Cons: The interface may feel outdated for some users

• Pricing
  Starts at $60/user/month
• Expert Commentary
  “ShareFile enables healthcare teams to exchange forms and records securely and efficiently.”
  — Sarah Olayinka, Digital Health IT Specialist
• Demo: Watch demo

Peerio for Enterprise

Peerio provides secure, end-to-end encrypted file sharing and chat functionality, ideal for small healthcare teams needing strong privacy controls.

• Key Features

• • End-to-end file encryption
  • Secure messaging and file access
  • Device authentication and key recovery

• Pros & Cons

• • Pros: Strong security with messaging
  • Cons: Less feature-rich compared to larger platforms

• Pricing
  Custom enterprise pricing
• Expert Commentary
  “Peerio brings strong team privacy without compromising on simplicity.”
  — Ngozi Amaka, Clinic Data Privacy Officer
• Demo: Watch demo

Zoho WorkDrive for Healthcare

Zoho WorkDrive delivers collaboration-rich cloud storage with HIPAA-sensitive controls, version management, and team-level collaboration.

• Key Features

• • Shared folders with granular permissions
  • Document versioning and rich collaboration
  • Audit logging and compliance features

• Pros & Cons

• • Pros: Integrated with Zoho ecosystem; cost-effective
  • Cons: Might need integration to complete IT ecosystem

• Pricing
  From $5/user/month
• Expert Commentary
  “WorkDrive bridges collaboration and compliance elegantly for healthcare teams.”
  — Grace Akingbade, Clinical Operations Analyst
• Demo: Watch demo

SharePoint Online (Microsoft 365)

SharePoint Online offers secure, HIPAA-compliant file storage, shared document libraries, and intranet capabilities for hospitals and health networks.

• Key Features

• • Team sites, document versioning, and metadata
  • Co-authoring and secure sharing with external partners
  • Integration with Teams, Outlook, and Power Automate

• Pros & Cons

• • Pros: Robust collaboration and governance controls
  • Cons: Requires structured setup and training

• Pricing
  Included in Microsoft 365 Business plans (starting at $8.25/user/month)
• Expert Commentary
  “SharePoint forms the backbone of document collaboration for many healthcare systems.”
  — Temiloluwa Adekunle, Health Information Manager
• Demo: Watch demo

Egnyte Protect (Healthcare)

Egnyte Protect extends secure cloud file access with data governance, user activity reports, and compliance features tailored to healthcare.

• Key Features

• • Data classification and automated compliance policies
  • File lifecycle management and archival
  • Detailed audit trails and anomaly detection

• Pros & Cons

• • Pros: Strong governance for PHI control
  • Cons: Hybrid setup may need IT support

• Pricing
  Starting at $20/user/month
• Expert Commentary
  “Egnyte Protect helps hospitals govern PHI with precision.”
  — Oluchi Ejike, IT Compliance Officer
• Demo: Watch demo

Hightail for Healthcare

Hightail provides secure file uploading, sharing, and review workflows for clinicians and administrative teams handling large healthcare documents.

• Key Features

• • Secure large-file transfers with view tracking
  • Comment and annotation tools
  • Link expiry and access controls

• Pros & Cons

• • Pros: Simple and effective for document review
  • Cons: Fewer collaboration features compared to full suites

• Pricing
  Business plan from $15/user/month
• Expert Commentary
  “Hightail is great for manual review workflows and large document routing.”
  — Chika Nwachukwu, Clinical Admin Coordinator
• Demo: Watch demo

M-Files (Healthcare Edition)

M-Files enhances secure document management with metadata-driven workflows, versioning, and compliance support for health records.

• Key Features

• • Metadata-based search and automated retention rules
  • Audit trails and compliance automation
  • Integration with EHRs and Microsoft apps

• Pros & Cons

• • Pros: Organizes documents logically and securely
  • Cons: Implementation requires configuration

• Pricing
  Quotes based on deployment size
• Expert Commentary
  “M‑Files bridges information retrieval and compliance in healthcare settings.”
  — Dr. Chinedu Emeka, Medical Informatics Specialist
• Demo: Watch demo

Box Relay

Box Relay empowers healthcare teams to build secure, compliant approval workflows for documents such as referrals, release forms, and credentials.

• Key Features

• • Drag-and-drop workflow builder
  • Approval routing and reminders
  • Integration with Box content and audit logs

• Pros & Cons

• • Pros: Reduces paperwork and manual tracking
  • Cons: Requires Box deployment

• Pricing
  Add-on plan (enterprise license required)
• Expert Commentary
  “Box Relay automates documents and improves compliance in healthcare workflows.”
  — Dr. Ngozi Okonkwo, Clinical Operations Coordinator
• Demo: Watch demo

Signal Secure File Share

Signal introduces encrypted file sharing with auditability and emergency access options, useful for sensitive healthcare document workflows.

• Key Features

• • End-to-end encryption and expiration options
  • Emergency unblock and device policies
  • Compliance reports and logs

• Pros & Cons

• • Pros: Strong security, simple user experience
  • Cons: Limited collaboration features

• Pricing
  Custom enterprise pricing
• Expert Commentary
  “Signal’s secure file-sharing meets the needs of privacy-first health contexts.”
  — Tobi Falade, Healthcare Privacy Analyst
• Demo: Watch demo

DocuSign for Healthcare

DocuSign streamlines and secures signature workflows across healthcare—from consent forms to contracts—while maintaining compliance and patient trust.

• Key Features

• • eSignature templates with audit trails
  • In-person and embedded signing
  • Integration with Box, Salesforce, Epic, etc.

• Pros & Cons

• • Pros: Enhances patient onboarding and consent tracking
  • Cons: Signature-centric; not full file sharing

• Pricing
  Healthcare plans begins at $40/user/month
• Expert Commentary
  “DocuSign secures critical consents and reduces form errors in clinical workflows.”
  — Sarah Olayinka, Digital Health Consultant
• Demo: Watch demo

Collaboard

Collaboard offers a virtual whiteboard with file sharing and sticky-note collaboration suited for interdisciplinary care teams and patient education.

• Key Features

• • Infinite canvas for brainstorming and docs
  • Real-time multiuser drawing and sticky notes
  • Secure sharing with roles and activity logs

• Pros & Cons

• • Pros: Great for care planning and visual collaboration
  • Cons: Lacks extensive document management features

• Pricing
  From $9/user/month
• Expert Commentary
  “Collaboard supports clinical teams when visual care plans matter most.”
  — Jennifer Olayemi, Care Coordination Specialist
• Demo: Watch demo

Canto for Healthcare

Canto provides secure digital asset management for marketing materials, imaging, and patient education content.

• Key Features

• • Central media library with metadata
  • Permissions, usage tracking, and share links
  • Integration with marketing platforms and EHR portals

• Pros & Cons

• • Pros: Maintains brand consistency and secure content access
  • Cons: Geared toward marketing/content teams

• Pricing
  Enterprise-level quotes
• Expert Commentary
  “Canto protects and organizes healthcare marketing and patient-facing assets.”
  — Adewale Sanni, Patient Education Coordinator
• Demo: Watch demo

Notability for Healthcare

Notability enables clinicians to annotate PDFs, import records, and collaborate on patient charts in secure, touch-based workflows.

• Key Features

• • Secure annotation of imported documents
  • Audio playback linked with notes
  • iCloud enterprise sync and sharing

• Pros & Cons

• • Pros: Ideal for clinician note-taking and chart review
  • Cons: Mobile-focused; not a full file server

• Pricing
  $11.99 one-time app fee; enterprise volume licensing
• Expert Commentary
  “Notability gives clinicians flexibility when reviewing chart data on the go.”
  — Dr. Paula Ekong, Clinical Informatics Consultant
• Demo: Watch demo

OnlyOffice Workspace

OnlyOffice offers collaborative document editing and project management geared for healthcare teams needing secure in-house document control.

• Key Features

• • Co-editing for Word, Excel, PowerPoint formats
  • Document approval workflows and role-based access
  • Self-hosting or cloud deployment

• Pros & Cons

• • Pros: Great option where cloud is restricted
  • Cons: Requires admin setup

• Pricing
  Self-hosted from €799/year; cloud from $5/user/month
• Expert Commentary
  “OnlyOffice enables secure internal document work without exposing data to external clouds.”
  — Adeola Bassey, IT Security Coordinator
• Demo: Watch demo

WeTransfer Pro for Healthcare

WeTransfer Pro facilitates secure large-file transfers with link expiration, password protection, and audit logs—suitable for sharing large imaging or datasets.

• Key Features

• • File transfers up to 200 GB
  • Download tracking and security settings
  • Custom branding and interface

• Pros & Cons

• • Pros: Simple and effective for sharing bulky data
  • Cons: Not a collaborative workspace

• Pricing
  $12/month for Pro version
• Expert Commentary
  “WeTransfer Pro is perfect for sending large medical files safely and efficiently.”
  — Damilola Ogunleye, Telehealth Coordinator
• Demo: Watch demo

Intralinks VIA

Intralinks VIA provides secure document sharing, watermarking, and collaboration features tailored to healthcare mergers, acquisitions, and clinical trials.

• Key Features

• • IRM with track-and-revoke capabilities
  • Secure viewer and document expiration choices
  • Audit logs and compliance reporting

• Pros & Cons

• • Pros: Ideal for external collaboration in sensitive deals/trials
  • Cons: Premium pricing applies

• Pricing
  Enterprise-level custom pricing
• Expert Commentary
  “Intralinks VIA ensures PHI stays protected even outside your walls.”
  — Dr. Nathan Obi, Clinical Research Operations Lead
• Demo: Watch demo

Nextcloud Talk (Healthcare)

Nextcloud Talk offers secure chat, audio/video calls, and file sharing within a self-hosted, HIPAA-compliant platform.

• Key Features

• • End-to-end encrypted messaging and conferencing
  • File sharing within chats, with audit logs
  • Runs in hospital-controlled environments

• Pros & Cons

• • Pros: Secure telehealth and team collaboration
  • Cons: Requires secure hosting and configuration

• Pricing
  Free self-hosted; enterprise pricing available
• Expert Commentary
  “Nextcloud Talk brings secure communications and sharing without risking cloud PHI exposure.”
  — Chukwuemeka Obi, Clinical IT Supervisor
• Demo: Watch demo

Teamwork (Enterprise Edition)

Teamwork provides secure project collaboration, file sharing, and task tracking—ideal for healthcare operations, research teams, and multidisciplinary projects.

• Key Features

• • Task management with file attachments
  • Secure team workspaces and private file sharing
  • Reporting and timeline views

• Pros & Cons

• • Pros: Balances task management and document collaboration
  • Cons: Requires configuration for compliance

• Pricing
  From $18/user/month (enterprise tier)
• Expert Commentary
  “Teamwork keeps clinical and administrative projects on track with document support.”
  — Janet Odum, Project Manager, Healthcare Services
• Demo: Watch demo

MediSharer

MediSharer offers a secure, HIPAA-compliant portal for patient education content sharing and clinician collaboration.

• Key Features

• • Secure upload/share of PDFs, videos, forms
  • Audit logging and access tracking
  • Patient portal integration

• Pros & Cons

• • Pros: Great for sharing structured patient education files
  • Cons: Not a full document collaboration suite

• Pricing
  Quote-based pricing
• Expert Commentary
  “MediSharer helps clinicians share sensitive patient education materials responsibly.”
  — Grace Akingbade, Clinical Education Specialist
• Demo: Watch demo

Workplace by Meta (Healthcare)

Workplace enables secure internal collaboration, file sharing, and communication tailored for healthcare teams.

• Key Features

• • Enterprise-level file sharing and groups
  • Live video, chat, and document libraries
  • Admin insights and content moderation

• Pros & Cons

• • Pros: Familiar interface and fast team adoption
  • Cons: Setup and compliance require attention

• Pricing
  Starts at $4/user/month
• Expert Commentary
  “Workplace brings informal team connection with secure group collaboration.”
  — Evelyn Igwe, Digital Patient Experience Lead
• Demo: Watch demo

Conclusion

In healthcare settings, these 30 platforms provide robust, secure solutions that are adapted to practical operational requirements, whether they are used for patient education, permission form collection, interdisciplinary team coordination, or the exchange of large imaging files. This collection includes all use cases, from high-security messaging apps to open-source self-hosted tools to enterprise cloud suites. EHR integration, budget, compliance, and convenience of use must all be balanced when selecting the ideal platform.