Top 15 Best Managed File Transfer Software for Clinics

Unlike regular file-sharing platforms, Managed File Transfer (MFT) software goes a step further by meeting the specific demands of the healthcare industry. These tools support the secure handling of sensitive patient data while also helping clinics keep up with strict data protection laws such as HIPAA. As clinics manage everything from electronic health records to lab reports and diagnostic images, they face increasing pressure to protect patient privacy, simplify how data moves between systems, and maintain full compliance.

MFT software offers a smarter way to handle these challenges. With strong encryption, built-in automation, detailed tracking, and compliance-ready features, the right solution can significantly. In this article, we’ve put together a list of 15 top managed file transfer software for clinics.

Top 15 Best Managed File Transfer Software for Clinics 

1. Virtru

Virtue Secure Share makes it easy for healthcare providers and patients to exchange sensitive PHI files safely. Instead of juggling multiple portals, remembering complex passwords, or installing new software, users can securely share information with just a few clicks. With built-in end-to-end encryption, the platform protects your data from the moment it’s sent to the moment it’s received. You also stay in control of your files. Data owners can decide who has access, for how long, and even track when someone views a file. If needed, they can revoke access or set expiration dates giving full visibility over shared information.

Pros

• Intuitive and user-friendly interface
• Strong customer support available when needed

Cons:

• Some users may find the instructions a bit unclear at first

What makes Virtue Secure Share especially convenient is how accessible it is. It puts simplicity first without sacrificing security.

2. Progress MOVEit

Progress MOVEit offers a comprehensive MFT solution designed to help healthcare organizations manage and protect sensitive data transfers. It ensures encryption of data both at rest and in transit, providing detailed audit logs to support HIPAA compliance. MOVEit’s automation capabilities streamline workflows, reducing manual intervention and the risk of human error. Its user-friendly interface allows for easy implementation and maintenance, making it a reliable choice for clinics aiming to enhance data security and operational efficiency. ​

Pros

• Reliable file transfers: Handles file sharing with consistent performance.
• Strong features: Offers a wide range of useful functions.
• Workflow automation: Cuts down on repetitive manual tasks.
• Secure transfers: Keeps sensitive data safe at all stages.

Cons

• Initial setup can be tricky: Some users report difficulty getting started.
• Integration hiccups: Connecting with other systems may require extra effort.
• Occasional security concerns: A few users noted vulnerabilities.

Progress MOVEit gives healthcare teams a solid way to manage file transfers while boosting data protection. Although it has a learning curve and some integration issues, many users still find it a practical solution for handling sensitive information securely.

3.  GoAnywhere MFT

GoAnywhere MFT helps healthcare organizations keep electronic Protected Health Information (ePHI) and EHR secure during file transfers. It uses secure protocols and encryption methods to protect sensitive data as it moves between systems. One of its key strengths is automation. By handling repetitive file transfer tasks automatically, it reduces the chances of manual errors. It also logs every activity in detail and generates reports, which can make compliance with HIPAA and HITECH less stressful for IT teams. The dashboard is simple to navigate, giving users a clear view and control over their file transfer processes in one place.

Pros:

• Automates file transfer tasks, reducing manual errors
• Offers detailed audit logs and reports to support compliance
• Centralized dashboard makes it easy to manage file transfers
• Handles data extraction, transformation, and integration

Cons:

• Lacks drag-and-drop functionality
• No built-in feature for tracking data lineage
• Scheduler setup can be tricky for some users

GoAnywhere also supports critical data operations such as data extraction, data transformation, and data integration, which are essential for maintaining clean and consistent information across systems.

4. Maytech Quatrix

Maytech’s Quatrix helps clinics send and receive medical files safely within a secure, HIPAA-compliant system. It uses end-to-end encryption to protect sensitive patient information during transfers. With full audit logs, clinics can track who accessed which files and when, making it easier to stay compliant with regulations. Quatrix also supports very large files like scans and x-rays without limits, making it useful for clinics managing high-volume or high-resolution data.

Pros

• Strong data protection during transfers
• Helps maintain HIPAA compliance with audit tracking
• Supports automated file transfers
• Handles large files like scans and x-rays with ease

Cons

• Higher pricing compared to basic file-sharing tools
• Initial setup or advanced features may feel complicated to some users

5.  Control- M

Control-M MFT helps businesses move files securely and reliably across different systems and locations. It supports multiple protocols and connects easily with existing business processes, making data transfers both efficient and compliant. For clinics, this solution proves especially helpful in sending confidential patient records, research files, and other sensitive documents securely.

Pros

• Users appreciate how fast and secure the transfers
• Control-M MFT also scales well and adapts to various platforms

Cons

• The API could use stronger security features.
• Licensing fees are on the higher side.
• Compatibility with newer applications needs attention.

6. Kiteworks

Kiteworks helps healthcare professionals send and receive files of any size from any device or location. It uses strong encryption and strict access controls to protect patient information and supports HIPAA compliance. The platform also connects with existing enterprise tools, making it easier for clinics to handle file transfers and collaboration securely.

Pros

• Integrates with enterprise systems
• Makes it simple to create, manage, and share a large number of documents
• User-friendly interface for most everyday tasks

Cons

• Navigating through many folders can feel cumbersome
• Managing file expiration settings can be tricky in complex folder structures

7. Serv-U by SolarWinds

Serv-U by SolarWinds stands out with its ability to support both on-premises and hybrid deployment. This flexibility appeals especially to healthcare organizations that need full control over their data storage and document sharing practices to meet HIPAA requirements. With Serv-U, users can manage file transfers securely while staying compliant with regulatory standards.

Pros

• Makes file sharing and project collaboration easier in a secure environment.
• Improves workflow efficiency by allowing users to automate tasks with event-based triggers.

Cons

• Some users find it difficult to configure the software for high-availability across multiple servers.
• Managing ports and gateways during setup can be complicated, especially in multi-host environments.

8. JSCAPE

JSCAPE MFT helps businesses automate operations by setting up specific triggers and protecting sensitive data like bank details using its data loss prevention features. It also supports compliance with HIPAA regulations. The platform is multilingual, offering support in English, Spanish, French, German, and Russian.

Pros

• Users value the different secure protocols available, including FTPS, SFTP, and SCP, which add an extra layer of protection during file transfers.
• Both clients and administrators find the web interfaces easy to use, making file transfers more efficient and straightforward.

Cons

• Under heavy workloads, the system may crash, which can lead to longer maintenance periods.
• The fixed size of some dialog windows makes the interface harder to navigate, which affects the overall user experience.

9. Cerberus FTP Server

Cerberus FTP Server gives healthcare organizations the flexibility to adjust their security settings according to their internal policies. This adaptability sets it apart from other HIPAA-compliant file-sharing platforms that follow a stricter, less flexible approach. To protect data during transfers, the server uses at least 128-bit encryption and also includes a FIPS 140-2 mode for organizations that require it. For tracking and compliance purposes, it logs all file activity, making it easier to meet regulatory requirements.

Pros:

• Meets HIPAA standards, which helps protect sensitive healthcare information
• Supports secure protocols like SFTP and HTTPS
• Includes detailed logging to assist with audits and compliance checks

Cons:

• Some users say it lacks strong controls for limiting how much data can be stored in individual folders

10. Stonebranch

Stonebranch MFT helps organizations move files safely across different IT environments, all while keeping in line with HIPAA compliance. It focuses on giving teams the tools to monitor and control their file transfers more effectively. By using centralized scheduling and monitoring tools, teams can keep track of transfers and reduce the chances of errors or data breaches.

Pros

• HIPAA Compliance: The platform supports secure transfer protocols and uses encryption to safeguard sensitive information.
• Improved Oversight: With a single point of control, users can consistently monitor and manage transfer activities.

Cons

• Challenging Setup: Getting started may take time and require support from experienced technical staff.
• Resource Demands: Larger operations might need more powerful systems to run the platform smoothly.

11. SmartFile

SmartFile works well across many systems and workflows common in healthcare, making it easier to share sensitive information while staying compliant with HIPAA regulations. It gives users precise control over who can access what, which helps protect patient data. Files are encrypted during transfer and storage, adding another layer of safety. The platform also tracks user activity and file movement, helping organizations keep tabs on how information is handled.

Pros:

• Many users find the FTP feature helpful for managing and backing up files.
• It offers generous file storage, which supports efficient data management.

Cons:

• Some users report that uploads can be slower than they’d like

12. FileCloud

FileCloud stands out for its simple, no-code setup, allowing users to create processes easily and access reports with just one click. It ensures HIPAA-compliant file sharing and enhances medical report sharing through built-in DICOM image previews. This makes it a valuable tool in healthcare settings, especially for handling large medical files and facilitating collaboration.

Cons

While FileCloud provides strong encryption, automatic virus scanning, and smart data loss prevention to protect sensitive information, some users might find these features more complex compared to other simpler solutions.

13. ShareFile

ShareFile is a secure platform for file sharing and collaboration, particularly beneficial for businesses, including those in the healthcare industry. It focuses on providing strong security with features like encryption, access controls, and the ability to remotely wipe data, which helps meet HIPAA requirements. Additionally, ShareFile works well with popular workplace tools and supports the transfer of large files, making it a flexible choice for clinics looking to manage their document workflows securely.

Pros

• ShareFile is easy to use and quick to set up.
• The platform offers customizable security settings to safeguard sensitive information.

Cons

• The file upload speed is slow and could use improvement.
• Its pricing is higher compared to some other options available in the market.

14. Files.com

Files.com is a cloud-based platform for securely transferring and sharing files within organizations, teams, and between businesses. It combines the core advantages of FTP software with the added security and automation features typically found in managed file transfer systems.

Pros:

• Onboarding is quick and simple for new users.
• It allows you to manage multiple cloud storage options in one place.
• The platform meets HIPAA and PCI compliance standards for secure file storage.

Cons:

• Files.com does not offer an on-premises solution for those who prefer local storage.
• The interface can be somewhat challenging to navigate for new users.
• Customization options are somewhat limited, restricting personalization.

15. Box

Box makes it easier to handle and organize your files by giving you one place to manage and share them. It supports faster collaboration and helps teams stay productive by letting them work together more easily. Since it works well with many popular apps, you can continue using the tools you’re familiar with while keeping your files stored safely in the cloud.

Pros

• Works well with a wide range of third-party applications
• Includes multiple compliance features for added security
• Offers a variety of plans to suit businesses of different sizes

Cons

• Mobile users may find editing options limited
• The editing tools within the platform can feel awkward to use
• New users might face a steep learning curve when getting started.

In today’s healthcare system clinics handle a growing amount of sensitive patient data. Choosing the right managed file transfer software has become more important than ever. It plays a key role in protecting patient information, improving daily operations, and ensuring that clinics meet necessary privacy regulations. A reliable MFT solution, clinics can safely exchange large data files, keep patient records confidential, and stay compliant with HIPAA guidelines. This choice also helps teams work better together, reduces delays in sharing critical information, and supports smoother day-to-day communication.

Ultimately, the right MFT software makes it easier for medical staff to focus on patient care. As a result, clinics not only improve their internal workflows but also deliver faster, more efficient service to their patients.

See related article: Top 15 Best Medical Data Security Software for Clinics