Top 30 Best Healthcare API Management Platforms
API management involves creating, testing, monitoring, securing, and analyzing APIs to help organizations connect systems and manage data flows more efficiently. These platforms are typically hosted on local servers, cloud environments, or a mix of both, depending on infrastructure needs. Healthcare API management platforms now play a central role across hospitals, health tech startups, and telemedicine providers. They support tasks such as syncing patient records, connecting diagnostic devices, and automating claims workflows.
Managing API platforms presents several hurdles. Organizations must comply with strict data regulations like HIPAA and GDPR. They also need to work with complex data formats such as HL7 and FHIR. On top of that, they must ensure consistent system availability while keeping sensitive information secure. These demands make healthcare API management platforms essential. These tools help teams control access, monitor traffic, track usage, and maintain clear documentation throughout the API lifecycle.
Top 30 Best Healthcare API Management Platforms
1. Cerner API
Cerner APIs allow healthcare applications to connect directly with Cerner’s electronic health record systems. This connection enables access to patient health records and essential administrative information, making it easier for developers to build apps that support clinical workflows.
These APIs make it possible to pull patient health information, integrate administrative data, and add features that support patient interactions. Developers can also use clinical decision support capabilities and tools that help manage and analyze healthcare data efficiently. In terms of security, Cerner provides data encryption, enforces HIPAA compliance, and includes monitoring features to keep patient information safe.
2. Veradigm
Veradigm offers a way for healthcare apps to connect with EHR systems and access critical clinical and administrative data. This connection helps developers build solutions that support hospitals and clinics in managing their operations more effectively. With Veradigm, healthcare services can securely access patient health information while maintaining strict data protection standards.
The platform brings together essential tools for handling administrative records, monitoring user behavior, and managing sensitive data. It includes engagement features and user analytics that help healthcare providers better understand how their systems are used. To protect this information, Veradigm supports strong encryption, role-based access, ongoing monitoring, and detailed audit logging, all of which contribute to maintaining privacy and compliance.
3. Meditech
Meditech offers APIs that simplify how healthcare apps connect with its electronic health records, especially for those focused on acute care and home health services. These APIs work well for mobile urgent care, elder care, and in-home health platforms, giving administrative teams a secure and organized view of patient history. The RESTful infrastructure supports safe access between Meditech’s system and third-party applications, making it easier to integrate without compromising patient information.
Once patients give permission, the API provides view-only access to their records, strictly for patient-centered workflows. It supports industry standards like USCDI V1 and DSTU2/R4, and full documentation is available through the website or Workspace web app. Meditech also offers FHIR-based scheduling APIs. These help unify appointment booking across different EHRs, ambulatory tools, and scheduling systems. This allows patients to book appointments more easily, no matter which provider or system they use.
4. Particle Health
Particle Health’s Management APIs help healthcare organizations control access and set up network permissions for entities requesting patient data. These APIs use patient demographics to search a vast network containing millions of medical records. Once a match is found, users can access consultation notes, lab results, and Continuity of Care Documents.
Adding Particle Health to a patient-focused application improves the way patients interact with insurance-related information. It helps manage claims, organize records, and track risk adjustments more effectively. The API meets security standards, holding SOC 2 certification and complying with both HIPAA regulations and OAuth 2.0 protocols.
5. Epic
Epic on FHIR, together with the open.epic framework, gives developers and healthcare systems a structured way to share and access patient data. The Epic Integration API makes it possible for different healthcare platforms to communicate and share updates quickly and securely. This steady flow of updated information helps doctors and care teams make informed decisions while reducing the risk of errors. It also supports data analysis, allowing providers to track patterns in care and spot opportunities to improve how they operate. Epic’s platform uses protective protocols that follow HIPAA standards, keeping patient information safe throughout the process.
6. Bluestream
Bluestream Health offers a flexible virtual care solution that healthcare providers can embed directly into their own applications. Its API allows organizations to connect with electronic medical records, billing tools, reporting systems, and more. Developers can build a fully branded experience within their own platform while gaining access to key features like video calls, screen sharing, image capture, and customizable forms. The platform supports notifications and data collection even when offline, making it useful in varied clinical environments. Ambulatory centers can configure the system to suit specific needs and monitor patient visits through unified reports. Hospitals use it to manage intake, triage, appointment scheduling, and patient queues across different departments. Meanwhile, clinics rely on it to update patient records, check vitals, review medications, and transition patients smoothly between staff members.
7. DrChrono
DrChrono’s API management platform gives healthcare developers the tools to build directly on its cloud-based EHR, billing, and practice management systems. Its REST API, which follows OAuth 2.0 standards, includes over 27 endpoints that cover everything from appointments and patient charts to lab orders and billing functions. This allows developers to connect easily in various programming environments.
Through a self-service portal, users can register their apps, manage credentials, and access software development kits, how-to guides, and community discussions. The platform also includes open APIs and webhooks to support lab integrations. These features support lab workflows, embedding through iFrames, and even offer fax as a backup method. This approach simplifies how clinical data is shared and integrated across systems.
8. Apigee
Apigee HealthAPIx offers a flexible solution for healthcare organizations looking to expand their digital services without being tied to a specific FHIR server. It gives hospitals, health plans, clinics, and life sciences companies the tools to securely manage and grow their APIs, helping them collaborate with app developers and data partners more effectively.
Healthcare providers can bring in data from various sources, whether internal systems or external FHIR-ready partners. This flexibility supports a faster rollout of patient-focused digital services, including mobile apps and secure data-sharing tools. With compliance built into the process, healthcare teams can confidently push forward with innovation while maintaining control and security.
9. MuleSoft
MuleSoft’s Anypoint Platform offers healthcare organizations a practical way to develop and integrate APIs within their systems. It brings together a wide set of tools that help users create, manage, and secure APIs from a single interface, supporting efforts across healthcare teams.
Healthcare providers and support teams can use the platform to improve how data moves between systems and applications. Components like CloudHub and Mule Enterprise Service Bus (ESB) help connect services both in the cloud and on-site. These tools make it easier to exchange data across different platforms, enabling teams to build APIs that draw from existing systems without starting from scratch. With Anypoint Connectors, healthcare companies can quickly connect with widely-used industry software and services. These connectors support standards such as HL7 and MLLP, allowing for compatibility with common healthcare protocols. For instance, teams can use pre-built integration templates to link accounting, billing, or marketing systems into a broader workflow. Because these connectors are built directly into the Anypoint Platform, teams can launch integrations faster, regardless of where their systems are hosted.
10. Redox
Redox Platform API offers healthcare organizations a practical way to automate internal workflows and keep a close eye on operations. It supports RESTful JSON calls, allowing teams to carry out administrative tasks like managing user access, configuring data sources and destinations, setting up filters, and retrieving log data. The platform handles high volumes of data traffic each year, and it’s built to remain stable even under pressure. With 99.95% uptime and HITRUST certification, it prioritizes reliability and security. It also includes built-in authentication tools, flexible communication options, smart traffic notifications, and automation features that simplify asset and workflow management.
11. OpenFDA Drug API
The OpenFDA Drug API makes it easier for developers and researchers to access drug-related data from the U.S. Food and Drug Administration through a web-based system. It helps users search and retrieve critical information about medications, including their official labels, approved usage, dosage instructions, warnings, and manufacturing details. You can look up specific drugs using identifiers like the drug name or National Drug Code (NDC). It also provides access to reports of adverse events and medication errors, offering insight into how drugs perform in real-world settings. In addition to drug data, the API supports connections to other FDA databases, such as the Food API and Device API, allowing for more comprehensive data access across different health-related categories.
12. athenahealth
athenahealth makes it easier for developers to build connected healthcare solutions through its flexible API frameworks. These tools support standard protocols like HL7 and C-CDA, which allow systems to share clinical data directly within the athenaOne interface or link up with other external platforms. In addition to these integrations, the platform includes features such as an analytics-ready data view on demand, options for exporting bulk data, and a dedicated function for structured transfers of both patient records and billing information. Together, these capabilities help developers create solutions that fit specific business needs while keeping data exchange efficient and secure.
13. Kong API
Kong’s API platform, often used alongside the Konga GUI, has gained traction in healthcare for its ability to connect various systems like ehrs, laboratory services, billing platforms, and pharmacies. It simplifies how healthcare organizations share and secure patient data, allowing faster access to records while also improving tasks such as scheduling and claims processing. The platform supports the entire API lifecycle, from design and deployment to governance and discovery, using tools like Kong Gateway, AI and Event Gateways, service mesh, analytics, and a developer-focused portal. Healthcare professionals appreciate how Kong supports HIPAA-compliant data sharing, reduces the complexity of operations, and helps teams bring new services to market more quickly. DevOps teams also benefit from the control it provides through CI/CD pipelines and hybrid-cloud environments.
14. Infermedica
Infermedica API simplifies how you bring intelligent medical features into your digital health platform. Built with input from experienced doctors and engineers, it helps you create smarter, faster patient interactions. The API analyzes patient messages instantly, identifying both medical and everyday terms for symptoms and conditions. It works well within chat-based interfaces, making it easy to build flows that gather information before a patient ever meets a healthcare provider.
You can collect key details such as demographics, symptom summaries, and medical history. It also creates pre-filled notes to give clinicians a clear overview before they even open a file. With these insights delivered early, your care team stays better informed and ready to act.
15. Amazon Comprehend Medical API
Amazon Comprehend Medical API uses natural language processing (NLP) to scan clinical texts and pull out key medical information in a way that’s easy to understand. It works across different document types, including electronic health records, doctor’s notes, radiology reports, and clinical trial files. When healthcare applications connect with this API, it becomes easier to automate updates for tasks like medical coding, prescription details, and appointment tracking, which reduces the need for manual input and saves time. It also supports secure handling of patient data, helping organizations meet HIPAA compliance while managing clinical workflows more efficiently.
16. TrueVault API
TrueVault helps healthcare organizations handle sensitive data while staying compliant with privacy laws like HIPAA and GDPR. It offers a secure way to store, manage, and access both structured and unstructured information without exposing it to unnecessary risks. Developers can use its API to encrypt data, control who gets access, and monitor every change or activity tied to that data. Instead of leaving files vulnerable, TrueVault keeps everything protected and only allows approved users to interact with the system. This approach reduces the chances of data breaches and helps safeguard against cyber threats.
17. Medable
Medable simplifies the development and management of digital health and clinical research tools through an API-first platform that brings together mobile apps, web portals, and trial workflows into a unified system. Developers can use the platform to build solutions that support clinical trials, from managing patient profiles and appointments to collecting and analyzing health data. Its App API allows teams to build applications with features like profile management, scheduling, and secure data handling. Additionally, the Patient Cloud API supports connections to third-party systems, making it easier to share information across healthcare networks. Medable gives researchers and healthcare providers a central way to build, manage, and connect digital trial experiences across different platforms.
18. BlueEHR
BlueEHR offers an electronic health record platform that supports healthcare providers in managing and organizing medical information in one place. Its adaptable structure makes it easy for teams to set up the system in a way that matches their specific workflow and preferences. The platform gives users access to a central hub where they can store, update, and view patient records without complications. Developers can also work with BlueEHR’s Clinical API to build tools that access or update clinical records, which helps simplify patient data handling across systems.
19. BetterDoctor
BetterDoctor offers a detailed database that helps users find doctors based on location, specialty, spoken language, and accepted insurance. The platform also allows users to book appointments online, check patient reviews, and receive visit reminders. Alongside these features, the BetterDoctor API gives developers the tools to build applications that can search for doctors, access their professional profiles, view schedules, and display patient ratings and insurance plan details. It makes it easier to create applications that connect users to the right healthcare professionals with the information they need to make informed choices.
20. Stripe
Stripe offers a payment processing solution that fits into healthcare applications, making it easier for providers to accept payments directly through their digital platforms. Healthcare organizations can use Stripe to collect payments for medical services and products, creating a smoother transaction process for patients.
The platform connects easily with electronic health records and other healthcare software systems. It includes fraud prevention tools to help reduce risk and supports flexible checkout forms that adapt to the needs of each organization. On the security side, Stripe protects transactions with TLS encryption and tokenization. It also complies with industry standards like PCI and HIPAA to help safeguard sensitive patient data.
21. Human API
Human API makes it easier for developers to access and use health data from different sources through a single interface. It pulls information from hospital records, lab tests, pharmacy medications, and even wearable fitness devices. This broad access gives apps and systems the ability to connect to a wide variety of health data without the usual complexity.
The platform handles connections with third-party data providers, manages user identities across systems, and ensures all information is organized in a consistent format. Everything runs through a secure RESTful API that meets HIPAA compliance standards, making it reliable for healthcare use. Instead of managing each data integration separately, developers can focus on building their apps while Human API manages the background work.
22. Lexigram
Lexigram helps healthcare professionals make sense of complex medical text by using machine learning to read and analyze documents like patient records, clinical reports, and research papers. Instead of simply skimming for keywords, the platform captures detailed context, offering deeper insights into patient information. With its intuitive interface, users can easily pull out specific data from medical notes while still retaining the context that’s critical to diagnosis and treatment. As a result, it becomes easier to spot trends, refine diagnoses, and support data-driven decisions across clinical and research environments.
23. Eligible
Eligible API allow healthcare applications to connect directly with insurance systems, making it easier to confirm policy details, check patient coverage, and verify authorizations. These APIs support the full insurance billing process, helping providers or their staff submit both in-network and out-of-network claims. Throughout the claims journey, from submission to final settlement, users can monitor progress through clearinghouses and revenue systems. Developers can also use APIs and webhooks to track billing events automatically from when a submission is created to when the payment is processed. This system helps eliminate manual steps and reduces the risk of errors. It works in sync with both insurance plans and healthcare systems, enabling faster verification and smoother billing, ultimately improving how providers manage payments and how patients experience care.
24. PYCAD
PYCAD focuses on AI-powered medical imaging solutions that help healthcare providers improve diagnostic accuracy and enhance operations. The company supports every stage of the development cycle, from data preparation and model training to deployment and integration. This approach makes them a valuable partner for hospitals, research institutions, and medical device companies seeking to apply AI in radiology. Their deep knowledge of medical imaging allows them to handle the complexities of this field, such as working with DICOM files, managing image annotations, and optimizing algorithms for modalities like X-ray, CT, and MRI. Their commitment to these specific use cases allows them to deliver meaningful outcomes in real clinical settings.
25. Microsoft Azure API for FHIR
Microsoft Azure API for FHIR helps healthcare organizations work more efficiently with data using the Fast Healthcare Interoperability Resources (FHIR) standard. It supports secure data exchange and storage while meeting industry regulations. Healthcare providers use it to improve how they share patient records across systems. Medical device makers rely on the API to build products that connect easily with existing digital health platforms. Tech companies in the healthcare space also use the service to create apps that communicate with other tools, encouraging better collaboration between systems. Researchers benefit from controlled access to FHIR data, allowing them to gather insights faster. Hospital IT teams find it useful for organizing patient records and making their workflows more efficient. Overall, Azure API for FHIR supports the move toward a connected healthcare environment by making data easier to access, share, and work with.
26. 1upHealth API
The 1upHealth API simplifies healthcare data integration by focusing on patient access and supporting FHIR interoperability standards. It gives developers and IT teams a way to connect with more than 10,000 healthcare systems, which opens up access to a large pool of patient data. This broad connectivity supports organizations looking to build compliant, patient-focused tools while meeting evolving healthcare regulations.
Hospitals and tech companies use it to create patient portals where individuals can view and manage their health records from different providers in one place. This improves visibility and encourages more active participation in their care. For researchers, the platform offers a way to gather and analyze anonymized patient data from multiple sources, helping drive faster discoveries and deeper insights across clinical studies.
27. IBM Watson
IBM webMethods API Management simplifies the entire API lifecycle, making it easier to create, manage, and secure APIs within a single platform. Users can develop integrations and instantly turn them into APIs without switching environments, which saves time and reduces complexity. It supports building a secure API ecosystem that encourages growth and helps businesses earn more from their digital products. The platform appeals to a broad set of users, including hospital IT teams, medtech firms, researchers, and healthcare device manufacturers. Its AI-powered tools for data analysis and image interpretation contribute to more efficient healthcare operations, helping users uncover valuable insights and improve collaboration.
28. SwaggerHub
SwaggerHub brings together API design and collaboration in one place, helping teams create consistent APIs more efficiently. It offers a smart editor that follows the latest Swagger standards, allowing users to catch errors early with helpful feedback and auto-suggestions. Teams can also preview how their APIs behave using built-in mocking tools, so they can test functions before writing any code. To maintain consistency across different APIs, SwaggerHub includes style validators and lets users store and reuse common syntax in shared domains. It also supports teamwork through a central workspace where developers can build new APIs together or find existing ones, all in a secure environment that encourages clear and organized collaboration.
29. Akana
Akana helps businesses take control of their APIs from start to finish. It allows teams to create, manage, and deploy APIs across different cloud environments while supporting broader digital initiatives. With Akana, companies can expose their data as APIs, link systems together more effectively, attract partners, monetize digital assets, and gain deeper insights into performance and operations. The platform also simplifies the design process with a visual interface, giving users the option to build APIs from the ground up or import existing specifications. Once the API design is complete, Akana automatically generates the required documentation formats, saving time and ensuring consistency.
30. Ideon
Ideon connects health insurance and benefits carriers with insurtech platforms using APIs that support fast and large-scale data exchange. Its API makes it possible to pull plan data into external tools like insurance platforms, broker systems, and healthcare apps. Users can access current details on rates, coverage options, and provider networks, making it easier to compare plans and support better decision-making.